About Hiʻa Ola

The Hi’a Ola Microbiome Test is co-founded by Professors Ruben Juarez and Alika Maunakea at the University of Hawai’i at Manoa, along with serial biotech entrepreneur Maitri Carmichael.

The Hi’a Ola Microbiome Test is co-founded by Professors Ruben Juarez and Alika Maunakea at the University of Hawai’i at Manoa, along with serial biotech entrepreneur Maitri Carmichael.

The Hiʻa Ola microbiome test

The Hiʻa Ola microbiome test is named after the Native Hawaiian words for “desire” and “life or health.” This at-home gut microbiome test helps people measure and manage their aging, helping them make informed decisions about their health and well-being. With Hiʻa Ola, monitoring your biological aging is as simple as collecting a stool sample using our easy-to-use kit, which is optimized to preserve the microbiome for analysis. Once your sample is processed, you get your results on a secure, user-friendly online dashboard that will give actionable insights into your aging process.

Discover how the Hiʻa Ola microbiome test can help you take control of your aging journey and embrace optimal health today.

The Hiʻa Ola microbiome test

The Hiʻa Ola microbiome test is named after the Native Hawaiian words for “desire” and “life or health.” This at-home gut microbiome test helps people measure and manage their aging, helping them make informed decisions about their health and well-being.

With Hiʻa Ola, monitoring your biological aging is as simple as collecting a stool sample using our easy-to-use kit, which is optimized to preserve the microbiome for analysis. Once your sample is processed, you get your results on a secure, user-friendly online dashboard that will give actionable insights into your aging process.

Discover how the Hiʻa Ola microbiome test can help you take control of your aging journey and embrace optimal health today.

Optimal longevity for all

Optimal longevity for all

Aging is a universal process, but the way we age—our biological age—is shaped by more than just the years on the calendar. Conditions like cardiovascular disease, diabetes, and neurodegenerative disorders remain leading causes of illness and death worldwide, highlighting the urgent need for innovative health solutions. Science now shows that biological aging, rather than chronological age, plays a critical role in determining our health span and susceptibility to disease.

At the cutting edge of this research lies the interplay between the gut microbiome and epigenetics—two powerful forces influencing the aging process. Emerging studies reveal that specific gut microbiome profiles are linked to DNA methylation patterns that regulate aging. These discoveries open up exciting new possibilities: by analyzing gut microbiome data, we can estimate biological age and uncover actionable insights for healthier aging.

Introducing the EpiBiome Clock and Hi’a Ola Microbiome Test
Our interdisciplinary team of experts in bioinformatics, microbiome research, epigenetics, and data science has developed the EpiBiome Clock—a groundbreaking algorithm that integrates gut microbiome data with epigenetic biomarkers to estimate biological age. Built using a unique database of paired microbiome and DNA methylation data, the EpiBiome Clock represents a major leap forward in personalized health technology.

Aging is a universal process, but the way we age—our biological age—is shaped by more than just the years on the calendar. Conditions like cardiovascular disease, diabetes, and neurodegenerative disorders remain leading causes of illness and death worldwide, highlighting the urgent need for innovative health solutions. Science now shows that biological aging, rather than chronological age, plays a critical role in determining our health span and susceptibility to disease.

At the cutting edge of this research lies the interplay between the gut microbiome and epigenetics—two powerful forces influencing the aging process. Emerging studies reveal that specific gut microbiome profiles are linked to DNA methylation patterns that regulate aging. These discoveries open up exciting new possibilities: by analyzing gut microbiome data, we can estimate biological age and uncover actionable insights for healthier aging.

Introducing the EpiBiome Clock and Hi’a Ola Microbiome Test
Our interdisciplinary team of experts in bioinformatics, microbiome research, epigenetics, and data science has developed the EpiBiome Clock—a groundbreaking algorithm that integrates gut microbiome data with epigenetic biomarkers to estimate biological age. Built using a unique database of paired microbiome and DNA methylation data, the EpiBiome Clock represents a major leap forward in personalized health technology.

Meet the team behind Hiʻa Ola

Ruben Juarez, PhD

Co-Founder

Chief Executive Officer of Hawai’i Integrated Analytics, HMSA Distinguished Endowed Professor at UH Economic Research Organization and Department of Economics at UH Mānoa.

Alika Maunakea, PhD

Co-Founder

Chief Scientific Officer of Hawai’i Integrated Analytics, Native Hawaiian, Professor in the Department of Anatomy, Biochemistry, and Physiology at University of Hawaii at Mānoa.

Maitri Carmichael

Co-Founder

2x biotech founder, previous companies acquired by Hitachi and 23andMe, helped commercialize the first at-home microbiome test at uBiome, degrees in molecular genetics and psychology. Maitri’s team includes Christian Patton on web development and Samantha Reda on graphic design.

Meet the team behind Hiʻa Ola

Ruben Juarez, PhD

Co-Founder

Chief Executive Officer of Hawai’i Integrated Analytics, HMSA Distinguished Endowed Professor at UH Economic Research Organization and Department of Economics at UH Mānoa

Alika Maunakea, PhD

Co-Founder

Chief Scientific Officer of Hawai’i Integrated Analytics, Native Hawaiian, Professor in the Department of Anatomy, Biochemistry, and Physiology at University of Hawaii at Mānoa

Maitri Carmichael

Co-Founder

2x biotech founder, previous companies acquired by Hitachi and 23andMe, helped commercialize the first at-home microbiome test at uBiome, degrees in molecular genetics and psychology.

Meet the team behind Hiʻa Ola

Ruben Juarez, PhD

Co-Founder

Chief Executive Officer of Hawai’i Integrated Analytics, HMSA Distinguished Endowed Professor at UH Economic Research Organization and Department of Economics at UH Mānoa

Alika Maunakea, PhD

Co-Founder

Chief Scientific Officer of Hawai’i Integrated Analytics, Native Hawaiian, Professor in the Department of Anatomy, Biochemistry, and Physiology at UH Mānoa

Maitri Carmichael

Co-Founder

2x biotech founder, previous companies acquired by Hitachi and 23andMe, helped commercialize the first at-home microbiome test at uBiome, degrees in molecular genetics and psychology. Maitri’s team includes Christian Patton on web development and Samantha Reda on graphic design.

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